Effect of Hemoadsorption for Cytokine Removal in Pneumococcal and Meningococcal Sepsis

Table 1

Patient characteristics, treatments, clinical parameters, and patient outcome. M: male, F: female, Cat-free: catecholamine-free, CRRT: continuous renal replacement therapy, SOFA: Sequential Organ Failure Assessment, and PELOD: Paediatric Logistic Organ Dysfunction (only case 4).

Case number	1	2	3	4	5
Sex	M	F	M	M	F
Age	40	66	40	14	36
Diagnosis	Pneumococcal Sepsis	Pneumococcal Sepsis	Meningococcal Sepsis (Serotype C)	Meningococcal Sepsis (Serotype C)	Meningococcal Sepsis (Serotype C)
Antibiotics	Ceftriaxone/ Vancomycin	Ceftriaxone/ Levofloxacin	Meropenem/ Amikacin/ Ceftriaxone	Dexamethasone/ Ceftriaxone	Levofloxacin / Ceftriaxone
Cytosorb treatments (n)	4	1	3	2	4
Cytosorb treatment time (h)	68	24	72	32	96
Delay (h)	<24	<15	15	11	8
SOFA Score/PELOD Score Admission	13	17	18	22	12
SOFA Score/PELOD Score Post treatment	10	20	16	13	8
Cat-free (days)	6	3	5	3	4
CRRT (days)	12	10	12	4	5
Ventilation (days)	20	53	10	4	5
ICU stay (days)	49	53	17	6	7
Amputation need	Yes/Phalange	Yes/Limbs	Yes/Phalanges	No	Yes/Toe
ICU mortality	No	Yes	No	No	No
28-day survival	Yes	Yes	Yes	Yes	Yes
Hospital mortality	No	Yes	No	No	No