Creutzfeldt-Jakob Disease Presenting as Expressive Aphasia and Nonconvulsive Status Epilepticus

Figure 1

EEG studies.

(a) Hospital day one to hospital day four: consistent with focal seizure activity from left hemisphere (frontal)

(b) Hospital day eight and day nine: continuous EEG revealed persistent epileptogenic activity with bilateral hemispheric discharges (left > right)

(c) Hospital day fourteen: 24 hours’ video EEG showing diffuse epileptiform discharge suggestive of encephalopathic state with presence of continuous left frontal and sometimes synchronized bifrontal sharp spikes with a more generalized appearance suggestive of NCSE

(d) Hospital day twenty-eight: EEG consistent with nonconvulsive status epilepticus (NCSE)