TY - JOUR A2 - Dinis-Oliveira, Ricardo Jorge AU - Bellefroid, CĂ©line AU - Goffin, Pierre AU - Guntz, Julien AU - Deville, Marine PY - 2020 DA - 2020/10/21 TI - Metformin-Induced Lactic Acidosis: A Question of Time SP - 6962591 VL - 2020 AB - Metformin is an oral antidiabetic largely prescribed in the treatment of type II diabetes. Overdose is associated with life-threatening lactic acidosis. We report the case of the highest metformin concentration ever described secondary to a voluntary suicidal intake. The patient developed a severe lactic acidosis and hemodynamic shock successfully treated with high-flow hemofiltration. Time to start extrarenal epuration is capital to avoid poor evolution. SN - 2090-6420 UR - https://doi.org/10.1155/2020/6962591 DO - 10.1155/2020/6962591 JF - Case Reports in Critical Care PB - Hindawi KW - ER -