Refractory Paraneoplastic Diarrhea Secondary to Adenocarcinoma of the Lung: A Case Report and Literature Review

Table 1

Patient’s stool studies	Normal values in parenthesis
Infectious disease
Stool leukocytes	No PMNs
Stool culture	Vibrio-negative
	Salmonella-negative
	Campylobacter-negative
	Shigella-negative
Clostridium difficile toxin PCR assay	Negative
Parasitic studies
Ova and parasites screen	Negative
Cryptosporidium/Giardia	Negative
Endocrine studies
5-HIAA, 24-hour urine	4.7 (<8 mg/24 hours)
ACTH	18.8 (6.0-59 pg/mL)
Cortisol (p.m.)	9.3 (2.0-14.0 ug/dL)
Calcitonin	229 (<7.6 pg/mL)
Chromogranin-A	152 (<92 ng/mL)
Gastrin	52 (0-180 pg/mL)
Serotonin	131 (<230 ng/mL)
Somatostatin	9 (up to 25 pg/mL)
VIP, plasma	Undetectable

Key: HIAA = 5-hydroxyindoleacetic acid, VIP = vasoactive intestinal peptide.