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Case Reports in Dentistry
Volume 2012, Article ID 247239, 4 pages
Case Report

Gorlin-Goltz Syndrome

1Sri Venkateshwara Dental College and Hospital, Kariyappanahalli, Anekal Road, Bannerughatta, Bangalore 560083, India
2Oral Medicine, Diagnosis and Radiology, Bangalore Institute of Dental Sciences, Lakkasandra, Wilson Garden, Bangalore, India
3Dayananda Sagar College of Dental Sciences, Shivage Malleshwara Hills, Kumarswamy Layout, Bangalore, India

Received 20 July 2012; Accepted 12 September 2012

Academic Editors: J. J. Segura-Egea and M. J. Wahl

Copyright © 2012 Padma Pandeshwar et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The Gorlin-Goltz syndrome (GGS) (the nevoid basal cell carcinoma syndrome—NBCCS) is a rare autosomal dominant syndrome caused due to mutations in the PTCH (patched) gene found on chromosome arm 9q. The syndrome, characterized by increased predisposition to develop basal cell carcinoma and associated multiorgan anomalies, has a high level of penetrance and variable expressiveness. GGS is a multidisciplinary problem, early diagnosis of which allows introduction of secondary prophylaxis and following an appropriate treatment to delay the progress of the syndrome. The following report emphasizes the need for awareness of the diagnostic criteria of this syndrome in cases with no typical skin lesions.