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Case Reports in Dentistry
Volume 2012, Article ID 257940, 4 pages
http://dx.doi.org/10.1155/2012/257940
Case Report

Mucormycosis of Mandible with Unfavorable Outcome

1Nitin Prakash Oswal, Sahyadri Hospital, Bopodi, Pune 411003, India
2Department of Oral and Maxillofacial Surgery, Sharad Pawar Dental College and Hospital, Sawangi Meghe, Maharashtra, Wardha, India
3Critical Care, Ruby Hall Clinic, Pune 411001, India
4Department of Oral and Maxillofacial Surgery, Bharati Vidyapeeth University, Dental College and Hospital, Katraj, Pune, India

Received 9 March 2012; Accepted 22 April 2012

Academic Editors: N. Brezniak and N. Yarom

Copyright © 2012 Nitin Prakash Oswal et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Mucormycosis is a fulminant fungal infection that occurs most often in diabetic and immunocompromised individuals. Our patient, with uncontrolled diabetes mellitus and multiple systemic disorders, developed postextraction mucormycosis of mandible, an extremely rare complication. An initial clinical and radiographic diagnosis of mandibular osteomyelitis was made and the lesion was treated medically and surgically with curettage and saucerisation. The specimen was sent for histopathological evaluation, which showed necrotic area containing broad aseptate fungal hyphae with right angle branching consistent with mucormycosis. The patient succumbed to multipleorgan failure secondary to septicemia. The disease is usually fatal with a poor survival rate; there is still paucity of literature on the definitive management of this disease involving the mandible. This paper emphasizes the need for correction of underlying immunodeficiency and early diagnosis with aggressive multimodality treatment approach to offer the best chance of survival.