Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Dentistry
Volume 2013 (2013), Article ID 410515, 7 pages
http://dx.doi.org/10.1155/2013/410515
Case Report

Porous Titanium Granules and Blood for Bone Regeneration around Dental Implants: Report of Four Cases and Review of the Literature

Department of Plastic & Oral and Maxillofacial Surgery, Institute of Surgical Sciences, Uppsala University, 751 85 Uppsala, Sweden

Received 14 January 2013; Accepted 11 February 2013

Academic Editors: M. A. Chinelatti and S. Nammour

Copyright © 2013 Andreas Thor. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. Esposito, M. G. Grusovin, P. Coulthard, and H. V. Worthington, “The efficacy of various bone augmentation procedures for dental implants: a Cochrane systematic review of randomized controlled clinical trials,” International Journal of Oral and Maxillofacial Implants, vol. 21, no. 5, pp. 696–710, 2006. View at Google Scholar · View at Scopus
  2. M. Chiapasco, P. Casentini, and M. Zaniboni, “Bone augmentation procedures in implant dentistry,” International Journal of Oral and Maxillofacial Implants, vol. 24, supplement, pp. 237–259, 2009. View at Google Scholar · View at Scopus
  3. M. Hallman and A. Thor, “Bone substitutes and growth factors as an alternative/complement to autogenous bone for grafting in implant dentistry,” Periodontology 2000, vol. 47, no. 1, pp. 172–192, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Lindhe and J. Meyle, “Peri-implant diseases: consensus report of the sixth European workshop on Periodontology,” Journal of Clinical Periodontology, vol. 35, no. 8, pp. 282–285, 2008. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Esposito, M. G. Grusovin, H. V. Worthington, and P. Coulthard, “Interventions for replacing missing teeth: bone augmentation techniques for dental implant treatment,” Cochrane Database of Systematic Reviews, no. 3, Article ID CD003607, 2006. View at Publisher · View at Google Scholar
  6. L. Holmberg, L. Forsgren, and L. Kristerson, “Porous titanium granules for implant stability and bone regeneration—a case followed for 12 years,” Upsala Journal of Medical Sciences, vol. 113, no. 2, pp. 217–220, 2008. View at Google Scholar · View at Scopus
  7. T. M. Turner, R. M. Urban, D. J. Hall, and G. B. J. Andersson, “Bone ingrowth through porous titanium granulate around a femoral stem: histological assessment in a six-month canine hemiarthroplasty model,” Upsala Journal of Medical Sciences, vol. 112, no. 2, pp. 191–197, 2007. View at Google Scholar · View at Scopus
  8. P. A. Alffram, L. Bruce, L. M. Bjursten, R. M. Urban, and G. B. J. Andersson, “Implantation of the femoral stem into a bed of titanium granules using vibration: a pilot study of a new method for prosthetic fixation in 5 patients followed for up to 15 years,” Upsala Journal of Medical Sciences, vol. 112, no. 2, pp. 183–189, 2007. View at Google Scholar · View at Scopus
  9. B. Jónsson and B. Mjöberg, “Surgical treatment of depression fractures of the lateral tibial plateau using porous titanium granules,” Upsala Journal of Medical Sciences, vol. 114, no. 1, pp. 52–54, 2009. View at Publisher · View at Google Scholar · View at Scopus
  10. J. C. Wohlfahrt, M. Monjo, H. J. Rønold, A. M. Aass, J. E. Ellingsen, and S. P. Lyngstadaas, “Porous titanium granules promote bone healing and growth in rabbit tibia peri-implant osseous defects,” Clinical Oral Implants Research, vol. 21, no. 2, pp. 165–173, 2010. View at Publisher · View at Google Scholar · View at Scopus
  11. H. Bystedt and L. Rasmusson, “Porous titanium granules used as osteoconductive material for sinus floor augmentation: a clinical pilot study,” Clinical Implant Dentistry and Related Research, vol. 11, no. 2, pp. 101–105, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. S. S. Jensen and H. Terheyden, “Bone augmentation procedures in localized defects in the alveolar ridge: clinical results with different bone grafts and bone-substitute materials,” International Journal of Oral and Maxillofacial Implants, vol. 24, supplement, pp. 218–236, 2009. View at Google Scholar · View at Scopus
  13. I. Darby, S. T. Chen, and D. Buser, “Ridge preservation techniques for implant therapy,” International Journal of Oral and Maxillofacial Implants, vol. 24, supplement, pp. 260–271, 2009. View at Google Scholar · View at Scopus
  14. C. E. Wen, Y. Yamada, K. Shimojima, Y. Chino, T. Asahina, and M. Mabuchi, “Processing and mechanical properties of autogenous titanium implant materials,” Journal of Materials Science, vol. 13, no. 4, pp. 397–401, 2002. View at Publisher · View at Google Scholar · View at Scopus
  15. J. C. Wohlfahrt, S. P. Lyngstadaas, L. Heijl, and A. M. Aass, “Porous titanium granules in the treatment of mandibular class ii furcation defects: a consecutive case series,” Journal of Periodontology, vol. 83, no. 1, pp. 61–69, 2012. View at Publisher · View at Google Scholar
  16. J. C. Wohlfahrt, S. P. Lyngstadaas, H. J. Rønold, E. Saxegaard, J. E. Ellingsen, and S. Karlsson, “Porous titanium granules in the surgical treatment of peri-implant osseous defects: a randomized clinical trial,” International Journal of Oral and Maxillofacial Implants, vol. 27, no. 2, pp. 401–410, 2012. View at Google Scholar
  17. R. Sabetrasekh, H. Tiainen, S. P. Lyngstadaas, J. Reseland, and H. Haugen, “A novel ultra-porous titanium dioxide ceramic with excellent biocompatibility,” Journal of Biomaterials Applications, vol. 25, no. 6, pp. 559–580, 2011. View at Publisher · View at Google Scholar
  18. P. E. P. Faria, A. L. Carvalho, D. N. B. Felipucci, C. Wen, L. Sennerby, and L. A. Salata, “Bone formation following implantation of titanium sponge rods into humeral osteotomies in dogs: a histological and histometrical study,” Clinical Implant Dentistry and Related Research, vol. 12, no. 1, pp. 72–79, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. J. Hong, K. Nilsson Ekdahl, H. Reynolds, R. Larsson, and B. Nilsson, “A new in vitro model to study interaction between whole blood and biomaterials. Studies of platelet and coagulation activation and the effect of aspirin,” Biomaterials, vol. 20, no. 7, pp. 603–611, 1999. View at Publisher · View at Google Scholar · View at Scopus
  20. A. Thor, L. Rasmusson, A. Wennerberg et al., “The role of whole blood in thrombin generation in contact with various titanium surfaces,” Biomaterials, vol. 28, no. 6, pp. 966–974, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. J. E. Davies and M. M. Hosseini, Histodynamics of Endosseous Wound Healing, EM Squared incorporated, Toronto, Canada, 2000.
  22. J. B. Cope and M. L. Samchukov, “Mineralization dynamics of regenerate bone during mandibular osteodistraction,” International Journal of Oral and Maxillofacial Surgery, vol. 30, no. 3, pp. 234–242, 2001. View at Publisher · View at Google Scholar · View at Scopus
  23. A. Thor, L. Sennerby, J. M. Hirsch, and L. Rasmusson, “Bone formation at the maxillary sinus floor following simultaneous elevation of the mucosal lining and implant installation without graft material: an evaluation of 20 patients treated with 44 Astra Tech implants,” Journal of Oral and Maxillofacial Surgery, vol. 65, no. 7, supplement, pp. 64–72, 2007. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Lundgren, S. Andersson, F. Gualini, and L. Sennerby, “Bone reformation with sinus membrane elevation: a new surgical technique for maxillary sinus floor augmentation,” Clinical Implant Dentistry and Related Research, vol. 6, no. 3, pp. 165–173, 2004. View at Google Scholar · View at Scopus
  25. M. B. Gorbet and M. V. Sefton, “Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes,” Biomaterials, vol. 25, no. 26, pp. 5681–5703, 2004. View at Publisher · View at Google Scholar · View at Scopus
  26. J. Hong, A. Azens, K. N. Ekdahl, C. G. Granqvist, and B. Nilsson, “Material-specific thrombin generation following contact between metal surfaces and whole blood,” Biomaterials, vol. 26, no. 12, pp. 1397–1403, 2005. View at Publisher · View at Google Scholar · View at Scopus
  27. J. Hong, J. Andersson, K. N. Ekdahl et al., “Titanium is a highly thrombogenic biomaterial: possible implications for osteogenesis,” Thrombosis and Haemostasis, vol. 82, no. 1, pp. 58–64, 1999. View at Google Scholar · View at Scopus
  28. J. E. Ellingsen, P. Thomsen, and S. P. Lyngstadaas, “Advances in dental implant materials and tissue regeneration,” Periodontology 2000, vol. 41, no. 1, pp. 136–156, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. F. Schwarz, M. Herten, M. Sager, M. Wieland, M. Dard, and J. Becker, “Bone regeneration in dehiscence-type defects at chemically modified (SLActive) and conventional SLA titanium implants: a pilot study in dogs,” Journal of Clinical Periodontology, vol. 34, no. 1, pp. 78–86, 2007. View at Publisher · View at Google Scholar · View at Scopus
  30. L. M. Bjursten, L. Rasmusson, S. Oh, G. C. Smith, K. S. Brammer, and S. Jin, “Titanium dioxide nanotubes enhance bone bonding in vivo,” Journal of Biomedical Materials Research Part A, vol. 92, no. 3, pp. 1218–1224, 2010. View at Publisher · View at Google Scholar · View at Scopus
  31. N. Ferraz, J. Carlsson, J. Hong, and M. K. Ott, “Influence of nanoporesize on platelet adhesion and activation,” Journal of Materials Science, vol. 19, no. 9, pp. 3115–3121, 2008. View at Publisher · View at Google Scholar · View at Scopus
  32. N. Ferraz, J. Hong, and M. Karlsson Ott, “Procoagulant behavior and platelet microparticle generation on nanoporous alumina,” Journal of Biomaterials Applications, vol. 24, no. 8, pp. 675–692, 2010. View at Publisher · View at Google Scholar · View at Scopus