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Case Reports in Dentistry
Volume 2013 (2013), Article ID 876503, 4 pages
http://dx.doi.org/10.1155/2013/876503
Case Report

Unusual Case of Inflammatory Myofibroblastic Tumor in Maxilla

1Department of Oral Pathology and Oral Radiology, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520 Turku, Finland
2Cell Biology Program, Research Institute, Hospital for Sick Children, University of Toronto, Room 7142, 555 University Avenue, Toronto, ON, Canada M5G 1X8
3Department of Oral and Maxillofacial Surgery, Institute of Dentistry, University of Turku, Lemminkäisenkatu 2, 20520 Turku, Finland
4Department of Pathology, University of Turku, Kiinanmyllynkatu 4-8, 20520 Turku, Finland

Received 5 February 2013; Accepted 25 March 2013

Academic Editors: D. W. Boston, L. N. De Souza, A. Markopoulos, and A. Milosevic

Copyright © 2013 Jaana Rautava et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Inflammatory myofibroblastic tumor (IMT) is a rare lesion found mostly in children and young adults and originates from the lung, abdominopelvic region, and retroperitoneum. Clinical manifestations of IMT or imaging are nonspecific and diagnosis is based on histopathological and immunohistochemical findings. Minority of all IMTs will metastasize. IMT in the oral cavity is an extreme rarity and this is a first case report of IMT in maxilla causing delayed tooth eruption and multiple cervical root resorption with an 11-year-old child. The IMT reported here was positive for smooth muscle actin, vimentin, and anaplastic lymphoma kinase (ALK1) with immunohistochemistry. Only three IMTs of the jaws have been reported so far and none of them had delayed root eruption and tooth resorption. This unusual case of IMT in a child was also ALK1- positive supporting neoplastic origin of her tumor. The case presented here underscores the importance of histopathological examination of the tissue found in any root resorption especially in the case of multiple resorptions.