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Case Reports in Dentistry
Volume 2014, Article ID 314391, 3 pages
Case Report

Ectodermal Dysplasia Associated with Sickle Cell Disease

Department of Post-Graduation, Master Program in Integrated Dentistry Science, University of Cuiabá, Avenida Manoel José de Arruda No. 3.100, 78050-000 Cuiabá, MT, Brazil

Received 20 June 2014; Revised 22 September 2014; Accepted 22 September 2014; Published 29 September 2014

Academic Editor: Ronald S. Brown

Copyright © 2014 Luiz Evaristo Ricci Volpato et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Ectodermal dysplasia and sickle cell anaemia are inherited disorders that affect, respectively, the tissues derived from the embryonic ectoderm and the production of erythrocytes by the bone marrow. The simultaneous occurrence of both disorders is extremely rare. This is a case of both ectodermal dysplasia and sickle cell anaemia reported in a 6-year-old. The patient had been diagnosed with sickle cell anaemia for only six months when he sought treatment presenting with the following: hypotrichosis, dry skin, periocular hyperpigmentation, protruding lips, hypodontia, and morphologically altered teeth. The clinical features combined with his medical history led to the diagnosis of ectodermal dysplasia. Dentists should be prepared to recognise patterns that escape normality to aid in the diagnosis of systemic changes, even in patients with other previous diagnoses.