Oral and Dental Findings of Dyskeratosis Congenita

Table 1

Multisystem clinical features of DC clinical feature/abnormality [4, 13].

	% of patients
Major/common features
Abnormal skin pigmentation	89
Nail dystrophy	88
BM failure	85.5
Leukoplakia	78
Other recognized somatic features
Epiphora	30.5
Learning difficulties/developmental delay/mental retardation	25.4
Pulmonary disease	20.3
Short stature	19.5
Extensive dental caries/loss	16.9
Esophageal stricture	16.9
Premature hair loss/greying/sparse eyelashes	16.1
Hyperhidrosis	15.3
Malignancy	9.8
Intrauterine growth retardation	7.6
Liver disease/peptic ulceration/enteropathy	7.3
Ataxia/cerebellar hypoplasia	6.8
Hypogonadism/undescended testes	5.9
Microcephaly	5.9
Urethral stricture/phimosis	5.1
Osteoporosis/aseptic necrosis/scoliosis	5.1
Deafness	0.8