|
| Author | Year | Anatomic location | Number of cases | | Clinical presentation | Microscopic findings |
| | Clinical features | Lesion size (mm) |
|
| | | Floor of the mouth | 32 | | Firm, nodular, pale pink, and up to 10 mm | ← | Hypertrophic oral tonsil
(i) Numerous enlarged lymphoid follicles with germinal centers
(ii) Single or a branched crypt which was lined with stratified squamous epithelium |
| Knapp [2] | 1970 | Ventral surface of the tongue | 5 | 52 total | Slightly compressible, yellowish “cystic” mass, creamy or cheese-like discharge, and up to 10 mm | ← | Tonsillar pseudocyst
(i) The lesion consisted of a cystic cavity which represented a dilated crypt lined with stratified squamous epithelium |
| | | Soft palate | 15 | | Red, firm rounded nodule, and from 1 to 3 mm | ← | Hyperemic oral tonsil
(i) It showed a prominent hyperemia of the tonsillar and peritonsillar blood vessels |
|
|
Wolter and Roosenberg [10] | 1977 | Orbit | 1 | | A smooth surface, an oval shape, and a rubber-like consistency | 24 × 15 × 10 | (i) Many primary lymphoid nodules with germinal centers |
|
| Paslin [5] | 1980 | Floor of the mouth | 1 | | Oval, pink, lucent, rounded, and firm papule on the sublingual fold just to the right of the frenulum. | 3 × 3 | (i) Circumscribed masses of lymphoid cells forming germinal centers surrounding the central crypt of stratified squamous epithelium |
|
| Pellettiere et al. [7] | 1980 | Larynx | 1 | | Firm and freely movable and covered by normal appearing, smooth, and intact mucosa | 15 | (i) Moderately well delineated germinal center |
|
| Furukawa et al. [9] | 1983 | Nasal septum | 1 | | Firm and greyish-white mass | 28 × 22 × 14 | (i) The surface epithelium of the tumour was fibrous tissue covered with squamous cells which invaginated into the lymphoid tissue producing crypts surrounded by lymphoid follicles |
|
| Mogi [3] | 1991 | Floor of the mouth | 1 | | Small, dark red, and soft tumor with no tender | 6 × 3 × 3 | (i) A germinal center surrounded by fibrous tissue invaded by squamous epithelium |
|
|
Patel et al. [4] |
2004 | Floor of the mouth | 1 | | Three small, red, and circular lesions in the mucosa of the floor of the mouth | 3 | (i) Aggregation of lymphoid tissue within the lamina propria
(ii) Well-defined lymphoid follicles |
| Ventral surface of the tongue | 1 | | White, soft, and nontender mucosal nodule of the frenum of the ventral surface of the tongue | 4 | (i) A focus of lymphoid tissue including follicles with well-formed germinal centers
(ii) A cystic lesion lined with stratified squamous epithelium filled with keratinous debris |
|
| Baba et al. [8] | 2010 | Hypopharynx | 1 | | Smooth mucosal swelling in the right pyriform recess | No mention | (i) Germinal center, lymphoid tissue, and crypt involving lymphoepithelial symbiosis |
|
| Kashima et al. [6] | 2012 | Floor of the mouth | 1 | | Well-circumscribed, smooth, round, painless, swelling covered by intact normal-appearing mucosa | 4 | (i) Abundant reactive lymphoid aggregates with well-formed germinal centers
(ii) A nondilated central crypt lined with stratified squamous epithelium and containing desquamated epithelial cells
(iii) Keratin debris in a central lacuna-like space |
|
|
Present cases (Kimura et al.) |
2014 | Ventral surface of the tongue | 1 | | Well-circumscribed, slightly red, hard on palpation, and bilateral presentation
A small pit was evident at the tip (Case 1) | 8/6 |
Shown in Table 2 |
| Floor of the mouth | 2 | | Well-circumscribed, slightly red, and hard on palpation (Case 2) | 5 |
| | Well-circumscribed and soft on palpation mass covered by normal mucosa (Case 3) | 6 |
|
