A Rare Case of Concomitant Maxilla and Mandible Brown Tumours, Papillary Thyroid Carcinoma, Parathyroid Adenoma, and Osteitis Fibrosa Cystica

Figure 1

(a)-(b) Clinical aspects of the maxilla and mandible lesions: haemorrhagic tumour masses involving the vestibular and lingual/palatal gingiva. (c) Radiographic aspects of the occlusal X-ray: large radiolucent area involving the teeth roots, with resorption (floating teeth). (d) Radiographic aspects of the lateral skull X-ray: evidence of an extensive bone loss in the mandible, resulting in a floating teeth appearance. (e) Sagittal CT scan image: expansive lesion with anterior displacement of the thyroid lobe and posterior contact with prevertebral muscles. (f) Coronal CT scan image: expansive lesions with central soft parts components and involvement of medial right maxillary sinus wall, alveolar and palatine processes up to the floor of the nasal fossa; the lesion is also seen in the right mandibular ramus and on the mentonian region, with involvement of the anterior teeth. (g)–(i) Histopathological aspects of the mandible lesion: the mass of multinucleated giant cells permeated by haemorrhagic infiltration next to the mandibular compact bone trabeculae (g); detail of multinucleated giant cells, fibroblasts, blood cells, and inflammatory infiltrate close to compact bone trabeculae (h); multinucleated giant cells and blood cells that compose the mandibular lesion (i). Haematoxylin and eosin, original magnification ×40, ×200, and ×400, respectively.

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