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Case Reports in Dentistry
Volume 2016, Article ID 6267406, 4 pages
Case Report

Medication-Related Osteonecrosis of Jaws: A Low-Level Laser Therapy and Antimicrobial Photodynamic Therapy Case Approach

1Dentistry Department, Oncology Research Center, Florianópolis, SC, Brazil
2Postgraduate Program in Dentistry, Federal University of Santa Catarina, Florianópolis, SC, Brazil
3Department of Morphological Sciences, Federal University of Santa Catarina, Florianópolis, SC, Brazil
4Department of Pathology, Ambulatory of Stomatology, University Hospital, Federal University of Santa Catarina, Florianópolis, SC, Brazil

Received 20 July 2016; Revised 15 August 2016; Accepted 22 August 2016

Academic Editor: Marília G. de Oliveira

Copyright © 2016 Mariana Comparotto Minamisako et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Medication-related osteonecrosis of the jaws (MRONJ) can be considered an inability of the alveolar bone to respond to an injury, which frequently leads to severe local and systemic complications. Once the problem is installed, dentist must use all therapeutic approaches recommended. This manuscript reports a successful management of MRONJ handled with antibiotics, conservative debridement, low-level laser therapy (LLLT), and photodynamic therapy (PDT) up to 12 months. As healing of MRONJ may be very slow, combined therapeutic approaches are required. Besides the recommended conventional treatment protocol, LLLT and PDT are important tools to contribute to healing and improvement of patient’s quality of life.