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Case Reports in Dermatological Medicine
Volume 2011, Article ID 324193, 2 pages
Case Report

Onychomadesis Developed Only on the Nails Having Cutaneous Lesions of Severe Hand-Foot-Mouth Disease

Department of Dermatology, Kyoto University, 54 Shogoin Kawaramachi Sakyo, Kyoto 606-8507, Japan

Received 19 November 2011; Accepted 10 December 2011

Academic Editors: M. Curzio, J.-H. Lee, J. Y. Lee, and M. Viglione

Copyright © 2011 Emi Shikuma et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


This paper reported a case of onychomadesis which appeared on the nails after heal of cutaneous lesions of hand-foot-mouth disease (HFMD). There were a few reports describing onychomadesis after HFMD; however, the mechanism is still unclear. The present case was prospectively observed, and onychomadesis was found to develop only on the nails having cutaneous lesions of HFMD. We considered that nail dysfunction due to direct inflammation spreading from skin eruptions around nail is one of the causes of onychomadesis linked to HFMD.