Dramatic Clinical Response of Relapsed Metastatic Extramammary Paget’s Disease to Trastuzumab Monotherapy

Figure 2

CT image of the metastatic lesion.

(a) Pretreatment CT showing a 13.4 × 11.8 mm metastasis in the lingulare superius of the left lung (black circle) and a 12.0 × 11.1 mm metastasis in segment VIII in the liver (white circle), pelvic, para-aortic lymphadenopathy, and mesenteric nodes collectively measuring 43.1 × 61.6 mm (arrow)

(b) CT following the tenth trastuzumab infusion showing decrease in the left lung lesion to 3 mm with complete resolution of all other measurable disease