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Case Reports in Dermatological Medicine
Volume 2012, Article ID 828749, 2 pages
Case Report

Erosive Pustular Dermatosis of the Scalp Induced by Imiquimod

1Unit of Dermatology, Pordenone Hospital, 33170 Pordenone, Italy
2Unit of Dermatology, University of Padua, 35128 Padua, Italy

Received 4 October 2012; Accepted 16 November 2012

Academic Editors: H. Dobrev, S. Kawara, and T.-W. Wong

Copyright © 2012 Maria Teresa Corradin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Erosive pustular dermatosis of the scalp (EPDS) is a rare condition characterized by sterile pustules, erosions, and crusted lesions on the scalp of elderly patients. This inflammatory disorder has an unknown origin and it could develop into areas of alopecia that tend to be atrophic. An 84-year-old Caucasian man presented with a several months history of painful erythematous erosions and crusts on his scalp. The lesions appeared after treatment with imiquimod cream for actinic keratoses. Previous therapies included topical antibiotics and topical steroids. Physical examination revealed the presence of extensive erosions and crusts on the scalp, with minute pustules on the sides. The clinical features and the medical history led us to the diagnosis of EPDS. Treatment with systemic steroid was administered with improvement observed after ten days. The clinical manifestations of EPDS completely resolved after 2 months, without clinical relapses.