Giant Congenital Melanocytic Naevus with Proliferative Nodules Mimicking Congenital Malignant Melanoma: A Case Report and Review of the Literature of Congenital Melanoma

Table 2

Seven melanoma-specific dermoscopic criteria [19]. As our case reports, a GCMN may show these features.

Criterion	Definition	Histopathologic correlates
(1) Atypical pigment network	Black, brown, or gray network with irregular meshes and thick lines	Irregular and broadened rete ridges
(2) Blue-whitish veil	Irregular, confluent, gray-blue to whitish-blue diffuse pigmentation	Acanthotic epidermis with focal hypergranulosis above sheets of heavily pigmented melanocytes in the dermis
(3) Atypical vascular pattern	Linear-irregular or dotted vessels not clearly combined with regression structures	Neovascularization
(4) Irregular streaks	Irregular, more or less confluent, linear structures not clearly combined with pigment network lines	Confluent junctional nests of melanocytes
(5) Irregular pigmentation	Black, brown, and/or gray pigmented areas with irregular shape and/or distribution	Hyperpigmentation throughout the epidermis and/or upper dermis
(6) Irregular dots/globules	Black, brown, and/or gray round to oval, variously sized structures irregularly distributed within the lesion	Pigment aggregates within stratum corneum, epidermis, dermoepidermal junction, or papillary dermis
(7) Regression structures	White areas (white scarlike areas) and blue areas (gray-blue areas, peppering, multiple blue-gray dots) may be associated, thus featuring so-called blue-whitish areas virtually indistinguishable from blue-whitish veil	Thickened papillary dermis with fibrosis and/or variable amounts of melanophages