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Case Reports in Dermatological Medicine
Volume 2013, Article ID 953840, 3 pages
Case Report

Porokeratotic Eccrine Ostial and Dermal Duct Nevus

1Department of Pathology, Razi Hospital, Tehran University of Medical Sciences, P.O. Box 14515-736, Tehran, Iran
2Department of Dermatology, Razi Hospital, Tehran University of Medical Sciences, P.O. Box 14515-736, Tehran, Iran

Received 31 August 2013; Accepted 2 October 2013

Academic Editors: A. Firooz, J. Y. Lee, and M. Viglione

Copyright © 2013 Mona Masoumeh Naraghi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


PEODDN is a rare benign cutaneous disorder that clinically resembles comedo nevus but favors the palms and soles, where pilosebaceous follicles are absent. Widespread involvement along Blaschko’s lines can also occur. It is a disorder of keratinization involving the intraepidermal eccrine duct (acrosyringium) and is characterized by eccrine hamartoma and cornoid lamellation in pathology. The patient is a 29-year-old man with an 8-year history of pruritic skin lesions on his right lateral ankle. In the pathologic examination, multiple small epidermal invagination with overlying parakeratotic cornoid lamellation, loss of granular layer, and few dyskeratotic cells at the base of epidermal invagination are revealed. After clinic-pathologic correlation, the diagnosis of porokeratotic eccrine ostial and dermal duct nevus (PEODDN) was made. Late-onset and rare clinical presentation as pruritic lesion are the characteristic features that make this patient an extraordinary presentation of PEODDN.