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Case Reports in Dermatological Medicine
Volume 2014, Article ID 853281, 4 pages
Case Report

Drug Reaction with Eosinophilia and Systemic Symptoms: DRESS following Initiation of Oxcarbazepine with Elevated Human Herpesvirus-6 Titer

1Department of Medicine, Tripler Army Medical Center, Honolulu, HI 96859, USA
2Dermatology Service, Tripler Army Medical Center, Honolulu, HI 96859, USA

Received 24 August 2013; Accepted 17 November 2013; Published 12 February 2014

Academic Editors: X.-H. Gao, S. Kawara, and I. Kurokawa

Copyright © 2014 Seth L. Cornell et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Drug reaction with eosinophilia and systemic symptoms (DRESS) is a rare and potentially fatal severe cutaneous reaction, which has a delayed onset after the initiation of an inciting medication. After recognition and withdrawal of the causative agent, along with aggressive management, a majority of patients will have complete recovery over several months. We present a rare case of DRESS secondary to oxcarbazepine with an elevated human herpesvirus-6 titer.