TY - JOUR A2 - Wong, Tak-Wah AU - Boisen, Julie AU - Malone, C. Helen AU - Kelly, Brent AU - Wagner, Richard F. PY - 2016 DA - 2016/05/16 TI - Cutaneous Squamous Cell Carcinoma with Invasion through Ear Cartilage SP - 9067428 VL - 2016 AB - Cutaneous squamous cell carcinoma of the ear represents a high-risk tumor location with an increased risk of metastasis and local tissue invasion. However, it is uncommon for these cancers to invade through nearby cartilage. Cartilage invasion is facilitated by matrix metalloproteases, specifically collagenase 3. We present the unusual case of a 76-year-old man with an auricular squamous cell carcinoma that exhibited full-thickness perforation of the scapha cartilage. Permanent sections through the eroded cartilage confirmed tumor invasion extending to the posterior ear skin. SN - 2090-6463 UR - https://doi.org/10.1155/2016/9067428 DO - 10.1155/2016/9067428 JF - Case Reports in Dermatological Medicine PB - Hindawi Publishing Corporation KW - ER -