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Case Reports in Dermatological Medicine
Volume 2017, Article ID 3240287, 4 pages
Case Report

Photopheresis Provides Significant Long-Lasting Benefit in Nephrogenic Systemic Fibrosis

Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI, USA

Correspondence should be addressed to William Nicholas Rose; gro.htlaehwu@esorw

Received 26 February 2017; Accepted 21 May 2017; Published 12 June 2017

Academic Editor: Alireza Firooz

Copyright © 2017 Ranran Zhang and William Nicholas Rose. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is a rare complication of exposure to gadolinium-based contrast agents in patients who have significantly decreased renal function. Manifestations include fibrosis of the skin and other tissues. Effective therapies are lacking. Photopheresis has been tried with variable rates of improvement, and small numbers of cases (20 as of 2016) have been reported of NSF patients treated with photopheresis. We report a case of patient with nephrogenic systemic fibrosis who was treated with photopheresis and demonstrated significant lasting improvements.