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Case Reports in Dermatological Medicine
Volume 2017, Article ID 3280215, 5 pages
Case Report

The Successful Treatment of a Case of Linear Psoriasis with Ixekizumab

1Saba University School of Medicine, The Bottom, Netherlands
2Icahn School of Medicine at Mount Sinai West, New York, NY, USA
3Icahn School of Medicine at Mount Sinai, New York, NY, USA

Correspondence should be addressed to Sara Ghoneim; ude.abas@mienohg.s

Received 10 August 2017; Accepted 10 October 2017; Published 2 November 2017

Academic Editor: Ravi Krishnan

Copyright © 2017 Sara Ghoneim et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Linear psoriasis is an unusual clinical variation of psoriasis that manifests segmentally along the lines of Blaschko. A major differential diagnosis is inflammatory linear verrucous epidermal nevus (ILVEN). The treatment of linear psoriasis is often challenging, with inadequate response to biological agents reported in the literature. We report a case of a 25-year-old African-American female who presented with asymptomatic hyperkeratotic papules along the lines of Blaschko and was subsequently diagnosed with linear psoriasis. After failing conventional treatment regimens, the patient received a trial of ixekizumab with complete resolution of cutaneous lesions reported after 4 months and only 8 doses of the anti-IL-17 biologic agent.