Case Report
Pravastatin-Induced Eczematous Eruption Mimicking Psoriasis
Table 1
Cases of pravastatin-induced adverse effects and P-glycoprotein interactions.
| Reported case of pravastatin-induced adverse effect | Other medications taken by patient | P-glycoprotein effect | References |
| Lichenoid drug eruption in 64-year-old woman [12] | Aspirin | Possible inducer | [13] | Candesartan | — | | Clopidogrel | Substrate | [9] | Diltiazem | Substrate, inhibitor, inducer | [9, 14] | Furosemide | — | | Hydralazine | — | | Isosorbide mononitrate | — | | Insulin | Inducer | [14] | Metformin | — | |
| Diffuse, pruritic rash in a 55-year-old woman [15] | Aripiprazole | Substrate | [16] | Lorazepam | — | | Sertraline | Substrate and inhibitor | [9, 14, 16] | Olanzapine | Substrate | [16] | Quetiapine | Substrate | [16] | Lithium carbonate | — | | Levothyroxine | Inducer | [17] | Magnesium | — | |
| Acute myopathy in a 65-year-old woman [18] | Aspirin | Possible inducer | [13] | Colchicine | Substrate, inducer | [14, 18] | Spironolactone | Inhibitor | [19] | Furosemide | — | | Losartan | Substrate, inhibitor | [9, 14] |
| Pruritic, psoriasis-like eczematous eruption in an 82-year-old man (current case) | Allopurinol | — | | Aspirin | Possible inducer | [13] | Colchicine | Substrate, inducer | [14, 18] | Hydrochlorothiazide | — | |
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