A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography

<div>A 33 mm Bowen’s disease lesion of the sternum (Patient 4). Cross-polarized photography is applied to enhance the visualization of the vascular pattern. Panel (a): the lesion at baseline. Panel (b): the area of the lesion at day 7 of treatment (one week after treatment onset with cryosurgery at day 0 and 4 daily applications of ingenol mebutate in days 0-3 of treatment). The white label is included for calibration purposes. Panel (c): the site of the lesion at 12 months follow-up. A slightly hypopigmented shallow scar is evident with excellent skin healing (hair follicle preservation) in a skin location of overall problematic healing features (sternum).</div>

Case Reports in Dermatological Medicine

fig1

Figure 1

Figure 1: A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography 

Figure 1 | A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography 