A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography

Figure 2

Dermoscopic images of the lesion acquired with the digital dermatoscope incorporated to the NITID device and the corresponding OCT image of Bowen’s lesion shown in Figure 1. The white line on the dermatoscopic image corresponds to the section scanned by OCT. Panels (a, b): the lesion at baseline. The left half of the OCT scan includes a healthy skin segment (control) featuring a well-defined epidermis (asterisk). At the transition of healthy skin to the lesion, the typical for Bowen’s disease thickening and disarrangement of the epidermis becomes evident (right to the arrow). Panels (b, d): the site of the lesions at the month follow-up. There is normalization of the epidermis in the dermoscopic and the OCT images (asterisk). The focal hyperkeratosis evident in the dermatoscopic image (Panel (b), arrow) is also evident in the OCT image as a disruption in the epidermis (Panel (d), arrow) which, however, causes no concern as the epidermis is homogenous throughout the scanned section.