Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Endocrinology
Volume 2011, Article ID 424712, 5 pages
http://dx.doi.org/10.1155/2011/424712
Case Report

Case of Hypercalcemia Secondary to Hypervitaminosis A in a 6-Year-Old Boy with Autism

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Washington University in Saint Louis and Saint Louis Children's Hospital, Saint Louis, MO 63110, USA

Received 2 June 2011; Accepted 13 July 2011

Academic Editors: H. G. Dorr and G. Nijpels

Copyright © 2011 Arpita Kalla Vyas and Neil H. White. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Kollars, A. E. Zarroug, J. Van Heerden et al., “Primary hyperparathyroidism in pediatric patients,” Pediatrics, vol. 115, no. 4, pp. 974–980, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  2. E. W. Shaw and J. Z. Niccoli, “Hypervitaminosis A: report of a case in an adult male,” Annals of internal medicine, vol. 39, no. 1, pp. 131–134, 1953. View at Google Scholar · View at Scopus
  3. O. Sakamoto, M. Yoshinari, T. Rikiishi et al., “Hypercalcemia due to all-trans retinoic acid therapy for acute promyelocytic leukemia: a case report of effective treatment with bisphosphonate,” Pediatrics International, vol. 43, no. 6, pp. 688–690, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. S. Fishbane, G. L. Frei, M. Finger, R. Dressler, and S. Silbiger, “Hypervitaminosis A in two hemodialysis patients,” American Journal of Kidney Diseases, vol. 25, no. 2, pp. 346–349, 1995. View at Google Scholar · View at Scopus
  5. R. G. Wieland, F. H. Hendricks, F. Amat y Leon, L. Gutierrez, and J. C. Jones, “Hypervitaminosis A with hypercalcaemia,” Lancet, vol. 1, no. 7701, p. 698, 1971. View at Google Scholar · View at Scopus
  6. C. M. Katz and M. Tzagournis, “Chronic adult hypervitaminosis A with hypercalcemia,” Metabolism, vol. 21, no. 12, pp. 1171–1176, 1972. View at Google Scholar · View at Scopus
  7. B. Frame, C. E. Jackson, W. A. Reynolds, and J. E. Umphrey, “Hypercalcemia and skeletal effects in chronic hypervitaminosis A,” Annals of Internal Medicine, vol. 80, no. 1, pp. 44–48, 1974. View at Google Scholar · View at Scopus
  8. G. Fisher and P. G. Skillern, “Hypercalcemia due to hypervitaminosis A,” Journal of the American Medical Association, vol. 227, no. 12, pp. 1413–1414, 1974. View at Publisher · View at Google Scholar · View at Scopus
  9. V. V. Ragavan, J. E. Smith, and J. P. Bilezikian, “Vitamin A toxicity and hypercalcemia,” American Journal of the Medical Sciences, vol. 283, no. 3, pp. 161–164, 1982. View at Google Scholar · View at Scopus
  10. S. C. Baxi and G. E. Dailey, “Hypervitaminosis A. A cause of hypercalcemia,” Western Journal of Medicine, vol. 137, no. 5, pp. 429–431, 1982. View at Google Scholar · View at Scopus
  11. K. Bhalla, D. M. Ennis, and E. D. Ennis, “Hypercalcemia caused by iatrogenic hypervitaminosis A,” Journal of the American Dietetic Association, vol. 105, no. 1, pp. 119–121, 2005. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  12. A. Kimmoun, B. Leheup, F. Feillet, F. Dubois, and A. Morali, “Hypercalcemia revealing iatrogenic hypervitaminosis A in a child with autistic troubles,” Archives de Pediatrie, vol. 15, no. 1, pp. 29–32, 2008. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus
  13. K. L. Penniston and S. A. Tanumihardjo, “The acute and chronic toxic effects of vitamin A,” American Journal of Clinical Nutrition, vol. 83, no. 2, pp. 191–201, 2006. View at Google Scholar · View at Scopus
  14. N. Binkley and D. Krueger, “Hypervitaminosis A and bone,” Nutrition Reviews, vol. 58, no. 5, pp. 138–144, 2000. View at Google Scholar · View at Scopus
  15. L. F. Bélanger and I. Clark, “Alpharadiographic and histological observations on the skeletal effects of hypervitaminoses A and D in the rat,” Anatomical Record, vol. 158, no. 4, pp. 443–451, 1967. View at Google Scholar · View at Scopus
  16. H. B. Fell and E. Mellanby, “Effects of hypervitaminosis A on foetal mouse bones cultivated in vitro; preliminary communication,” British Medical Journal, vol. 2, no. 4678, pp. 535–539, 1950. View at Google Scholar · View at Scopus
  17. C. M. Rohde and H. DeLuca, “Bone resorption activity of all-trans retinoic acid is independent of vitamin D in rats,” Journal of Nutrition, vol. 133, no. 3, pp. 777–783, 2003. View at Google Scholar · View at Scopus
  18. M. N. Megson, “Is autism a G-alpha protein defect reversible with natural vitamin A?” Medical Hypotheses, vol. 54, no. 6, pp. 979–983, 2000. View at Publisher · View at Google Scholar · View at PubMed · View at Scopus