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Case Reports in Endocrinology
Volume 2012, Article ID 586056, 2 pages
Case Report

Severe Hypothyroidism Causing Pre-Eclampsia-Like Syndrome

1Department of Obstetrics and Gynecology, San Raffaele Scientific Institute, Milan, Italy
2Department of Endocrinology and Internal Medicine, San Raffaele Scientific Institute, Milan, Italy

Received 2 February 2012; Accepted 3 April 2012

Academic Editors: C. Capella and A. Sahdev

Copyright © 2012 Annalisa Inversetti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. Analyzing and managing pre-eclampsia-like syndrome due to severe hypothyroidism. Methods. Presentation of a case of severe hypothyroidism due to Hashimoto’s syndrome, associated with a severe early-onset preeclampsia-like syndrome, managed in our Gynecology Department. Results. Severe pre-eclampsia led to miscarriage at 24 weeks of gestational age in a 42-year-old woman, although we attempted to correct hypothyroidism with increasing doses of levothyroxine and liothyronine sodium. Conclusion. Recognizing pre-eclampsia-like syndrome caused by overt hypothyroidism from other forms of pregnancy-induced hypertension is essential for choosing the correct treatment.