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Case Reports in Endocrinology
Volume 2012 (2012), Article ID 762023, 3 pages
Case Report

Secondary Pulmonary Hypertension and Right-Sided Heart Failure at Presentation in Grave’s Disease

Department of Medicine, Grant Medical College and Sir J.J. Group of Hospitals, Mumbai 400008, India

Received 27 September 2012; Accepted 15 October 2012

Academic Editors: M. A. Boyanov and S. Simsek

Copyright © 2012 Swapnil Panjabrao Ganeshpure et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A young female presented with evidence of right-sided heart failure and was subsequently found to have significant pulmonary artery hypertension (PAH). Because of her normal left ventricular function and pulmonary capillary wedge pressure, the most probable site of etiology seemed to be the pulmonary vasculature. All the common possible secondary causes of PAH were ruled out, but during the investigations, she was found to have elevated thyroid function tests compatible with the diagnosis of Grave’s disease. The treatment of Grave’s disease, initially by medications and subsequently by radioiodine therapy, was associated with a significant reduction in the pulmonary artery systolic pressure. The purpose of this case report is to highlight one of the unusual and underdiagnosed presentations of Grave’s disease.