Case Report

Tumor-Induced Osteomalacia: Increased Level of FGF-23 in a Patient with a Phosphaturic Mesenchymal Tumor at the Tibia Expressing Periostin

Table 1

Laboratory data of the patient before and after resection of the giant cell tumor.

Laboratory value (normal range)Before resection2 days after resection2 months after resection26 months after resection29 months after resectionLast follow-up, 34 months after resection

FGF-23 c-terminal (0.026–0.110 RU/mL or 20–70 pg/mL0.396 (+)0.037 (normal)NormalNormalNormalNormal
Phosphate (2.6–4.5 mg/dL)1.95 (−)n.p.NormalNormal2.14 (−)Normal
Calcium (8.5–10.1 mg/dL)NormalNormalNormalNormalNormalNormal
Alkaline phosphatase (40–129 U/L)305 U/L276 U/L178 U/LNormalNormalNormal
Bone specific alkaline phosphatase (<75%)79.6%n.p.n.p.n.p.NormalNormal
1.25-(OH)2D (16–81 pg/mL)4.83 (−)n.p.NormalNormalNormalNormal
25-(OH)-D (20–60 ng/mL)21 (normal)n.p.17.3 (−) NormalNormalNormal
Parathyroid hormone (15–65 ng/L)NormalNormalNormalNormalNormalNormal

n.p. = not performed.