Case Report
A Rare Presentation of Transfusional Hemochromatosis: Hypogonadotropic Hypogonadism
Table 1
Laboratory results of the case.
| | | | Reference range |
| | CBC parameters | | | WBC (103/μL) | 11.8 | 4.8–10.8 | | Hb (g/dL) | 8.9 | 12–16 | | HCT (%) | 27.3 | 37–47 | | RBC (103/μL) | 3.05 | 4.2–5.4 | | MCV (fL) | 89.5 | (80–94) | | MCH (g/dL) | 29.4 | 32–36 | | RDW (%) | 17.4 | 10–20 | | PLT (103/μL) | 1239 | 130–400 |
| | Hormonal measurements | | | FSH (μIU/mL) | 1.39 | 3.03–8.08 | | LH (μIU/mL) | 0.75 | 2.39–6.6 | | Estradiol (pg/mL) | <10 | 21–251 | | Progesterone (mg/mL) | 0.2 | 0–0.3 | | GH (ng/mL) | 2.53 | (0–8) | | Somatomedin-C (ng/mL) | 151 | (90–271) | | ACTH (pg/mL) | 43.2 | (0–46) | | Cortisol (μg/dL) | 15.9 | (3.7–19.4) | | Prolactin (mg/mL) | 9.29 | (5.2–26.5) | | sT3 (pg/mL) | 3.64 | 1.71–3.71 | | sT4 (ng/dL) | 1.21 | 0.7–1.48 | | TSH (μIU/mL) | 1.38 | 0.35–4.94 | | PTH (pg/mL) | 95.7 | 15–68.3 | | 25-OH-vitamin D (ng/mL) | 11.9 | 15–60 |
| | Biochemical measurements | | | Glucose (mg/dL) | 81 | 65–95 | | Cre (mg/dL) | 0.63 | 0.7–1.3 | | AST (U/L) | 18 | 0–31 | | ALT (U/L) | 15 | 0–31 | | GGT (U/L) | 16.3 | 5–36 | | ALP (U/L) | 245 | 0–270 | | T. bil (mg/dL) | 2.8 | 0.2–1.2 | | D. bil (mg/dL) | 0.44 | 0–0.5 | | T. prot (g/dL) | 7.5 | 6.6–8.7 | | Alb (g/dL) | 5 | 3.5–5.2 | | Ca (mg/dL) | 9.7 | 8.5–10.5 | | Iron (μg/dL) | 239 | 37–145 | | Ferritin (ng/mL) | 887 | 4.6–204 | | TIBC (μg/dL) | 357 | 215–480 |
| | Dynamic tests | | | | LHRH stimulation test (0, 30, 60, 90, and 120 min): | | | | FSH (μIU/mL): 1.14–1.33–1.41–1.72 | | | | LH (μIU/mL): 0.75–0.75–0.80–0.91 | | | | Insulin tolerance test: | | | | Peak GH: 11.6 ng/mL | | | | Peak cortisol: 26.3 μg/dL | | |
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For follicular phase.
For age 26–30.
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