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Case Reports in Endocrinology
Volume 2016, Article ID 4852907, 4 pages
http://dx.doi.org/10.1155/2016/4852907
Case Report

An Ectopic ACTH Secreting Metastatic Parotid Tumour

1University Hospital of Wales, Cardiff, UK
2Department of Diabetes & Endocrinology, Royal Glamorgan Hospital, Mid Glamorgan CF72 8XR, UK
3Royal Gwent Hospital, Newport, UK

Received 11 November 2015; Revised 21 December 2015; Accepted 22 December 2015

Academic Editor: Hidetoshi Ikeda

Copyright © 2016 Thomas Dacruz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. H. E. Turner and J. A. H. Wass, Oxford Handbook of Endocrinology and Diabetes, Oxford University Press, Oxford, UK, 2nd edition, 2009.
  2. T. A. Howlett, P. L. Drury, L. Perry, I. Doniach, L. H. Rees, and G. M. Besser, “Diagnosis and management of ACTH-dependent Cushing's syndrome: comparison of the features in ectopic and pituitary ACTH production,” Clinical Endocrinology, vol. 24, no. 6, pp. 699–713, 1986. View at Publisher · View at Google Scholar · View at Scopus
  3. F. A. Shepherd, J. Laskey, W. K. Evans, P. E. Goss, E. Johonsen, and F. Khamsi, “Cushing's syndrome associated with ectopic corticotropin production and small-cell lung cancer,” Journal of Clinical Oncology, vol. 10, no. 1, pp. 21–27, 1992. View at Google Scholar · View at Scopus
  4. L. R. Salgado, M. C. B. Villares Fragoso, M. Knoepfelmacher et al., “Ectopic ACTH syndrome: our experience with 25 cases,” European Journal of Endocrinology, vol. 155, no. 5, pp. 725–733, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. R. C. Smallridge, K. Bourne, B. W. Pearson, J. A. Van Heerden, P. C. Carpenter, and W. F. Young, “Cushing's syndrome due to medullary thyroid carcinoma: diagnosis by proopiomelanocortin messenger ribonucleic acid in situ hybridization,” Journal of Clinical Endocrinology and Metabolism, vol. 88, no. 10, pp. 4565–4568, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. E. H. Al Ojaimi, “Cushing's syndrome due to an ACTH-producing primary ovarian carcinoma,” Hormones, vol. 13, no. 1, pp. 140–145, 2014. View at Google Scholar · View at Scopus
  7. M. Sugawara and G. A. Hagen, “Ectopic ACTH syndrome due to salivary gland adenoid cystic carcinoma,” Archives of Internal Medicine, vol. 137, no. 1, pp. 102–105, 1977. View at Publisher · View at Google Scholar · View at Scopus
  8. V. V. Shenoy, Z. Lwin, A. Morton, and J. Hardy, “Ectopic adrenocorticotrophic hormone syndrome associated with poor prognosis in metastatic parotid acinic cell carcinoma,” Otolaryngology—Head and Neck Surgery, vol. 145, no. 5, pp. 878–879, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. L. Jamieson, S. M. Taylor, A. Smith, M. J. Bullock, and M. Davis, “Metastatic acinic cell carcinoma of the parotid gland with ectopic ACTH syndrome,” Otolaryngology—Head and Neck Surgery, vol. 136, no. 1, pp. 149–150, 2007. View at Publisher · View at Google Scholar
  10. V. Alcantara, E. Urgell, J. F. Sancho, and A. Chico, “Severe ectopic cushing syndrome caused by adenoid cystic carcinoma of a salivary gland,” Endocrine Practice, vol. 19, no. 5, pp. e118–e121, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. B. L. Wajchenberg, B. B. Mendonca, B. Liberman et al., “Ectopic adrenocorticotropic hormone syndrome,” Endocrine Reviews, vol. 15, no. 6, pp. 752–787, 1994. View at Google Scholar · View at Scopus
  12. J. P. Aniszewski, W. F. Young Jr., G. B. Thompson, C. S. Grant, and J. A. Van Heerden, “Cushing syndrome due to ectopic adrenocorticotropic hormone secretion,” World Journal of Surgery, vol. 25, no. 7, pp. 934–940, 2001. View at Publisher · View at Google Scholar · View at Scopus
  13. J. Newell-Price, P. Trainer, M. Besser, and A. Grossman, “The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states,” Endocrine Reviews, vol. 19, no. 5, pp. 647–672, 1998. View at Publisher · View at Google Scholar · View at Scopus
  14. C. Invitti, F. P. Giraldi, M. de Martin, and F. Cavagnini, “Diagnosis and management of Cushing's syndrome: results of an Italian multicentre study. Study Group of the Italian Society of Endocrinology on the pathophysiology of the Hypothalamic-Pituitary-Adrenal axis,” The Journal of Clinical Endocrinology & Metabolism, vol. 84, no. 2, pp. 440–448, 1999. View at Google Scholar
  15. D. C. Aron, H. Raff, and J. W. Findling, “Effectiveness versus efficacy: the limited value in clinical practice of high dose dexamethasone suppression testing in differential diagnosis of adrenocorticotropin-dependent Cushing`s syndrome,” Journal of Clinical Endocrinology and Metabolism, vol. 82, no. 6, pp. 1780–1785, 1997. View at Google Scholar · View at Scopus
  16. G. Reimondo, P. Paccotti, M. Minetto et al., “The corticotrophin-releasing hormone test is the most reliable non-invasive method to differentiate pituitary from ectopic ACTH secretion in Cushing's syndrome,” Clinical Endocrinology, vol. 58, no. 6, pp. 718–724, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. B. L. Wajchenberg, B. B. Mendonça, B. Liberman, M. A. A. Pereira, and M. A. Kirschner, “Ectopic ACTH syndrome,” The Journal of Steroid Biochemistry and Molecular Biology, vol. 53, no. 1–6, pp. 139–151, 1995. View at Publisher · View at Google Scholar · View at Scopus
  18. W. W. de Herder and S. W. J. Lamberts, “Tumor localization—the ectopic ACTH syndrome,” Journal of Clinical Endocrinology and Metabolism, vol. 84, no. 4, pp. 1184–1185, 1999. View at Google Scholar · View at Scopus
  19. P. M. Stewart, S. Gibson, S. R. Crosby et al., “ACTH precursors characterize the ectopic ACTH syndrome,” Clinical Endocrinology, vol. 40, no. 2, pp. 199–204, 1994. View at Publisher · View at Google Scholar · View at Scopus
  20. A. C. Hale, G. M. Besser, and L. H. Rees, “Characterization of pro-opiomelanocortin-derived peptides in pituitary and ectopic adrenocorticotrophin-secreting tumours,” Journal of Endocrinology, vol. 108, no. 1, pp. 49–56, 1986. View at Publisher · View at Google Scholar · View at Scopus
  21. T. Hara, H. Akutsu, T. Yamamoto, E. Ishikawa, M. Matsuda, and A. Matsumura, “Cushing's disease presenting with gastrointestinal perforation: a case report,” Endocrinology, Diabetes & Metabolism Case Reports, vol. 11, Article ID EDM130064, 2013. View at Publisher · View at Google Scholar
  22. K. Piekarek and L. A. Israelsson, “Perforated colonic diverticular disease: the importance of NSAIDs, opioids, corticosteroids, and calcium channel blockers,” International Journal of Colorectal Disease, vol. 23, no. 12, pp. 1193–1197, 2008. View at Publisher · View at Google Scholar · View at Scopus
  23. P. J. Coates, I. Doniach, T. A. Howlett, L. H. Rees, and G. M. Besser, “Immunocytochemical study of 18 tumours causing ectopic Cushing's syndrome,” Journal of Clinical Pathology, vol. 39, no. 9, pp. 955–960, 1986. View at Publisher · View at Google Scholar · View at Scopus
  24. L. K. Nieman, B. M. Biller, J. W. Findling et al., “Treatment of Cushing's syndrome: an endocrine society clinical practice guideline,” The Journal of Clinical Endocrinology & Metabolism, vol. 100, no. 8, pp. 2807–2831, 2015. View at Publisher · View at Google Scholar