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Case Reports in Endocrinology
Volume 2016, Article ID 9071097, 5 pages
Case Report

Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis

1Internal Department, Hospital de Segovia, Segovia, Spain
2Internal Department, Hospital Universitario Río Hortega, Valladolid, Spain
3Pathology Department, Hospital Universitario Río Hortega, Valladolid, Spain

Received 19 November 2015; Accepted 10 March 2016

Academic Editor: Osamu Isozaki

Copyright © 2016 Marta Gonzalez Rozas et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism.