Case Report

Effects of Mifepristone on Nonalcoholic Fatty Liver Disease in a Patient with a Cortisol-Secreting Adrenal Adenoma

Table 1

Baseline patient characteristics and laboratory findings.

ParameterResult

Age, years49
BMI, kg/m230.6
BP, mmHg142/90
HbA1c, mmol/mol41
Lipids, mmol/L
 Total cholesterol7.1
 LDL5.3
 TG1.5
Liver function
 AST, U/L (normal 2–40)110
 ALT, U/L (normal 2–60)232
Endocrine evaluation
 UFC, nmol/d (normal 11–138)172.8
 1-mg DST, nmol/L (normal < 49.5)364.3; 345.0
 Late night salivary cortisol, nmol/L
(normal < 2.5)
5.2
 ACTH, pmol/L (normal 1.1–9.9)<1.1 × 2
 DHEA-S, μmol/L (normal 1.1–7.9)0.54

ACTH, adrenocorticotropic hormone; ALT, alanine transaminase; AST, aspartate transaminase; BMI, body mass index; BP, blood pressure; DHEA-S, dehydroepiandrosterone sulfate; DST, dexamethasone suppression test; HbA1c, glycated hemoglobin A1c; LDL, low-density lipoprotein; TG, triglyceride; UFC, urinary free cortisol.