Acute Hyperglycemia Due to Topical Corticosteroid Administration

Table 1

Comparison of the current case with other cases of hyperglycemia related to topical corticosteroid use.

	Patient Information	Duration of Diabetes	Details of Topical Corticosteroid Use	Glycemic Control	Diabetes Regimen Prior	Diabetes Medications During Hyperglycemic Period
Current case	71 year old Caucasian man with type 1 diabetes	45 years	Psoriasis treated in the preceding 2 days with fluocinonide 0.1% cream (class I steroid)	A1C 5.9-7.4% in the prior 10 years	Insulin pump: 73 units total daily dose	Insulin via pump and subcutaneous injections: 356 units in 24 hours
Hongo et al 2017	80 year old Japanese man with type 2 diabetes	16 years	Psoriasis treated with class III-class V steroids over a 7-8 week period	First admission: A1C 8-9%; second admission 10 days later: A1C 7.6%	Lispro insulin 42 units per day, voglibose 0.9 mg per day	First admission: insulin increased to a maximum of 36 units of neutral protamine Hagedorn (NPH) insulin and 38 units of lispro insulin per day; second admission: insulin 32 units per day (dosing by insulin type not specified)
Kahara et al 2016	68 year old Japanese man with no history of diabetes	-----	Oral lichen planus treated with class VII steroid on the oral mucosa over a 6 month period	A1C 10.8% on admission after developing thirst and polyuria	-----	Alogliptin 25 mg daily started 2 months after diagnosis of diabetes and continued for 2 months