Dapagliflozin-Induced Acute Pancreatitis: A Case Report and Review of Literature

Table 1

Published case reports for SGLT-2 inhibitor-induced pancreatitis in the literature.

Author	SGLT-2 inhibitor	Age/sex	Ethnicity	Other reported medications	Time from medication administration until pancreatitis	Severity (description) and outcome
Patel et al. [14]	Canagliflozin	71/F	Not specified	Metformin, sitagliptin	84 days	Necrotizing pancreatitis, resolved
Chowdhary et al. [15]	Canagliflozin	33/F	African-American	Metformin, levothyroxine	14 days	Severe acute pancreatitis, resolved
Srivali et al. [16]	Canagliflozin	50/M	White	Metformin, glyburide	10 days	Acute pancreatitis precipitating DKA, resolved
Verma [17]	Canagliflozin	46/F	White	Metformin, insulin, lisinopril, lovastatin, citalopram, estradiol, oxybutynin	21 days	Moderately severe acute pancreatitis, resolved
Gutch et al. [18]	Dapagliflozin	48/M	Indian	Metformin	7 days	Acute pancreatitis precipitating DKA, resolved
McIntire and Bayne [19]	Empagliflozin	70/M	African-American	Insulin, HCTZ, lisinopril, atenolol, ibuprofen, ranitidine, simvastatin, simethicone	104 days	Mild pancreatitis, resolved
Lightbourne et al. [20]	Empagliflozin	52/F	Not specified	Metformin, insulin, furosemide	30 days	Acute pancreatitis, resolved