Case Report
Severe Hypothyroidism Complicated by Myopathy and Neuropathy with Atypical Demyelinating Features
Table 1
Results of initial laboratory tests (September 2019).
| | Parameters | Parameter value | Reference interval |
| | Sodium (mmol/L) | 140 | 135–145 | | Potassium (mmol/L) | 4.0 | 3.5–5.2 | | eGFR (mL/min/1.73 m2) | >90 | >90 | | Fasting glucose (mmol/L) | 3.9 | 3.0–5.5 | | Albumin (g/L) | 46 | 33–48 | | Alanine aminotransferase (U/L) | 197 | <51 | | Aspartate aminotransferase (U/L) | 345 | <36 | | Alkaline phosphatase (U/L) | 45 | 30–110 | | γ-Glutamyl transferase (U/L) | 12 | 5–50 | | Bilirubin (μmol/L) | 6 | 0–20 | | Corrected calcium (mmol/L) | 2.3 | 2.1–2.6 | | Magnesium (mmol/L) | 0.95 | 0.7–1.1 | | Phosphate (mmol/L) | 1.25 | 0.75–1.5 | | Holotranscobalamin (pmol/L) | 42.8 | 50.1–165 | | Folate (nmol/L) | 19.3 | 8.83–60.8 | | Creatine kinase (U/L) | 20,804 | 45–250 | | Total cholesterol (mmol/L) | 7.9 | 3–5.5 | | Free T4 (pmol/L) | 1.6 | 12–22 | | Free T3 (pmol/L) | <1.5 | 3.1–6.8 | | TSH (mIU/L) | 405.5 | 0.27–4.2 | | Haemoglobin (g/L) | 142 | 130–180 | | Platelets (×109/L) | 270 | 150–450 | | White cell count (×109/L) | 7.67 | 3.5–11 | | Thyroid peroxidase (TPO) antibodies (IU/mL) | >600 | ≤35 | | Thyroglobulin antibodies (IU/mL) | 152 | 0–115 | | Intrinsic factor antibodies | Negative | | | Gastric parietal cell antibodies | Negative | | | Antinuclear antibodies | Negative | | | Double stranded DNA antibodies | Negative | | | ENA screen | Not detected | | | Myositis antibodies screen | Not detected | | | Antimyelin-associated glycoprotein | Not detected | | | Acetylcholine receptor antibodies | Not detected | |
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Values in bold represent abnormal results
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