Persistent vs Recurrent Cushing’s Disease Diagnosed Four Weeks Postpartum

Table 1

24-hour urine-free cortisol measurements collected approximately every 8 weeks throughout our patient’s pregnancy.

Time in relation to pregnancy	4 months before conception and 2 months pre-TSA	2 weeks before conception and 7 weeks post-TSA	10 weeks	17 weeks	29 weeks	36 weeks	4 weeks postpartum
24-hour urine-free cortisol (μg/24 hr); nonpregnant reference range (LabCorp): 6–42 μg/24 hr	825.6	5	34	93	29	15	408

Pregnancy reference ranges have not been well established. UFC levels are typically higher in pregnancy, up to twice the upper limit of normal. Our patient was therefore said to have low UFC levels at 36 weeks gestation.