Case Reports in Emergency Medicine / 2017 / Article / Tab 1

Case Report

Tissue Hypoperfusion, Hypercoagulopathy, and Kidney and Liver Dysfunction after Ingestion of a Naphazoline-Containing Antiseptic

Table 1

Summary of clinical characteristics of naphazoline intoxication.

ReferenceAgeSexEstimated naphazoline intake (mg)SymptomsTreatmentTime before presentation (h)Outcome

[1]1F0.2Bradycardia, miosis hypothermia, conscious disturbance, bradypneaClose monitorN/RSurvival

[2]1MN/RConscious disturbance, miosisClose monitor1Survival

[2]2F3Bradypnea, conscious disturbance, miosisClose monitor11Survival

[3]1M4Hypertension, prolonged awaking from general anesthesia, pulmonary edemaMechanical ventilationN/RSurvival

[4]5M100Bradycardia, conscious disturbance, diaphoresis, hypothermiaDiuretics1.5Survival

[5]7MN/RBradycardia, conscious disturbance, convulsion, headache, miosis, nausea/vomitingClose monitorN/RSurvival

[6]89M70Bradycardia, bradypnea, conscious disturbance, diaphoresis, hypertension, hypothermiaMechanical ventilation, doxapram1Survival

[7]24MN/RConscious disturbance, diaphoresis, nausea/vomiting, premature ventricular beats, headacheMonitoring0.5Survival

[7]29MN/RBradycardia, cerebral hemorrhage, conscious disturbance, diaphoresis, ectopic ventricular beat, headache, nausea/vomitingEvacuation of cerebral hemorrhage atropine3Survival

[8]53MN/RHypertension, pulmonary edemaMechanical ventilation4Survival

[8]40MN/RDiaphoresis, headache, hypertension, nausea/vomiting, pulmonary edemaO2 via mask, doxapram1Survival

[8]32MN/RBradycardia, conscious disturbance, diaphoresis, hypertension, pulmonary edemaNicardipine, mechanical ventilation2Survival

[9]40M140Bradycardia, hypertension, pulmonary edemaAtropine, nicardipine, diuretics, doxapram, O2 via mask2Survival

[10]21F150Bradycardia, kidney dysfunction, liver dysfunction, miosis, pulmonary edema, QT elongationRenal replacement therapy, mechanical ventilation, siverastat, urinastatin3Survival

[11]23M150Kidney dysfunction, liver dysfunction, nausea/vomitingRenal replacement therapy, diuretics30Survival

Current case22F160Bradycardia, hypercoagulopathy, kidney dysfunction, liver dysfunction, nausea/vomitingRenal replacement therapy, Alprostadil72Survival

N/R, not recorded.