Case Report

Severe Enoral Bleeding with a Direct Oral Anticoagulant after Tooth Extraction and Heparin Bridging Treatment

Table 1

Coagulation tests on emergency department admission.

ParameterNorm valuesOn admission

INR0.7–1.21.13
PT (s)10–1211.7
aPTT (s)25–3637.9
Thrombin time (s)15.5–19.417.6
Fibrinogen (g/L)1.75–3.753.19
Low molecular weight heparin (LMWH) anti-Xa (AntiXa/mL)0.6–1.0 (at 4 hours after injection)1.02 (at >24 hours after injection)
Apixaban anti-Xa (ng/mL)No anticoagulant effect <3064.89

Activated partial thromboplastin time (aPTT); International normalised ratio (INR); Prothrombin time (PT).