An Adolescent with a Rare De Novo Distal Trisomy 6p and Distal Monosomy 6q Chromosomal Combination

Figure 4

Proposed complex NAHR mechanism. The yellow arrows represent the LCRs, and the black lines indicate the possible exchange of two dissimilar regions of 6p and 6q that may carry an LCR in the same orientation. A crossover could lead from A to e to f,which would result in a duplication of A and a deletion of d. Image created and derived from reference [21].