A Novel Use of Early Radiation Therapy in the Treatment of Hyperbilirubinemia in a Patient with Primary Hepatic Lymphoma and Chronic Hepatitis C

Table 3

𝑛 = PHL + jaundice	Age, sex	Lesion	T bili; mg/dL	Histology	Treatment	Outcome	Reference
1	67, M	Multiple nodules in liver	20.87	DLBCL	R-CHOP	Died after 4th cycle due to ARDS	Ma et al. [19]
1	62, M	Large solitary right hepatic lobe mass	N/M	DLBCL	None	Died 3 months after tumor diagnosis	DeMent et al. [4]
2	53, M	Diffuse	N/M	Pleiomorphic small cell*	Prednisolone and later multiagent chemotherapy	Died of disease at 18 months	Anthony et al. [5]
	76, M	Diffuse	N/M	T zone*	Prednisolone and chlorambucil	Alive and well at 3 years
2	49, M	Nodular	N/M	B cell type	8 cycles of anthracycline containing CT^#	CR at 52 months	Emile et al. [6]
1	90, F	Single mass in left lobe	2.3	DLBCL	4 cycles of attenuated CHOP	CR at 2 years	Agmon-Levin et al. [7]
1	55, F	Presented as biliary stricture with tumor in caudate lobe and left lobe of the liver invading CBD and occluding portal vein	3.4	DLBCL	Surgery followed by 6 cycles of CHOP + VP 16	Alive after 4.5 years after surgery	Yoneyama et al. [8]

N/M: not mentioned; M: male; F: female; CT: chemotherapy; DLBCL: diffuse large B cell lymphoma; *based on Kiel’s classification subtype; ^#complete chemotherapy regimen not mentioned; CR: complete remission; VP 16: etoposide, ARDS: acute respiratory distress syndrome, T bili: total bilirubin, mg/dL: milligram/deciliter, PHL: primary hepatic lymphoma; R-CHOP: rituximab, cyclophosphamide, adriamycin, vincristine, and prednisone; CBD: common bile duct.