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Case Reports in Gastrointestinal Medicine
Volume 2015 (2015), Article ID 125718, 4 pages
http://dx.doi.org/10.1155/2015/125718
Case Report

Rapid Progression of Primary Sclerosing Cholangitis Complicated with Ulcerative Colitis

1Department of Internal Medicine, Institute of Rural Health, 20-090 Lublin, Poland
2Department of Clinical Endoscopy, Institute of Rural Health, 20-090 Lublin, Poland
3Department of Public Health and Social Medicine, University of Rzeszów, 35-959 Rzeszów, Poland

Received 16 November 2014; Accepted 10 January 2015

Academic Editor: Hideto Kawaratani

Copyright © 2015 Piotr Pardak et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Primary sclerosing cholangitis is a cholestatic condition with unknown etiology and long-standing, progressive course, leading to cirrhosis and requiring orthotropic liver transplant. In approximately 80%, primary sclerosing cholangitis is accompanied by inflammatory bowel disease, and in most cases the recognition of bowel disease precedes the diagnosis of primary sclerosing cholangitis. We describe a case of 22-year-old male diagnosed simultaneously with primary sclerosing cholangitis and ulcerative colitis, with a medical history suggesting uncommon prior development of the liver disease. Five months after the initial diagnosis, we observed advanced lesions of bile tree due to progression of primary sclerosing cholangitis, which led to the unusually fast necessity for the orthotopic liver transplant.