Case Report

Treatment of Hepatic Epithelioid Hemangioendothelioma: Finding Uses for Thalidomide in a New Era of Medicine

Figure 2

(a) Replacing hepatocytes is tumor with sometimes large, often spindled, aberrant nuclei amid abundant light pink, feathery matrixes (H&E, 100x). (b) Uniformly dark, cancerous nuclei, sometimes huge, lie in variably colored cytoplasm, often not evident. Cancer cells lie in isolation and in epithelioid groups. At the arrowhead, a group lies about a vacuole, which is a vascular lumen (H&E, 400x). (c) Cancer cell cytoplasm often expresses CD34, which emphasizes the epithelioid pattern (DAB, 400x). (d) Many cancer cell nuclei, often juxtaposed to vacuoles, express Factor XIIIa (DAB, 400x). Gold bars are 200 μ long.
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