Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Gastrointestinal Medicine
Volume 2015, Article ID 405695, 4 pages
http://dx.doi.org/10.1155/2015/405695
Case Report

Intestinal Amyloidosis in Common Variable Immunodeficiency and Rheumatoid Arthritis

1Gastroenterology Department, Hospital Garcia de Orta E.P.E., Avenida Torrado da Silva, 2801-951 Almada, Portugal
2Rheumatology Department, Hospital Garcia de Orta E.P.E., Avenida Torrado da Silva, 2801-951 Almada, Portugal
3Anatomical Pathology Department, Hospital Garcia de Orta E.P.E., Avenida Torrado da Silva, 2801-951 Almada, Portugal

Received 14 March 2015; Revised 23 July 2015; Accepted 26 July 2015

Academic Editor: Özlem Yönem

Copyright © 2015 T. Meira et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We present a case of reactive amyloidosis that developed secondary to common variable immunodeficiency and rheumatoid arthritis. A 66-year-old woman, with prior history of common variable immunodeficiency and rheumatoid arthritis, was referred to our clinic for chronic diarrhea investigation. The patient was submitted to colonoscopy with ileoscopy, which did not show relevant endoscopic alterations. However, undertaken biopsies revealed amyloid deposition. Since amyloidosis with GI involvement is a rare cause of chronic diarrhea, this pathology should be considered in etiologic investigation, especially when associated with chronic inflammatory diseases.