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Case Reports in Gastrointestinal Medicine
Volume 2015, Article ID 869746, 8 pages
Case Report

Fulminant Hepatic Failure Secondary to Primary Hepatic Angiosarcoma

1Department of Medicine, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USA
2Department of Medicine, Section of Digestive Diseases and Nutrition, Oklahoma University Health Sciences Center, Oklahoma City, OK 73104, USA
3Department of Pathology, John H. Stroger Jr. Hospital of Cook County, Chicago, IL 60612, USA

Received 11 December 2014; Accepted 7 February 2015

Academic Editor: Haruhiko Sugimura

Copyright © 2015 Ayokunle T. Abegunde et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Background. Hepatic angiosarcoma is a rare and aggressive tumor that often presents at an advanced stage with nonspecific symptoms. Objective. To report a case of primary hepatic angiosarcoma in an otherwise healthy man with normal liver function tests two months prior to presenting with a short period of jaundice that progressed to fulminant hepatic failure. Methods. Case report and review of literature. Conclusion. This case illustrates the rapidity of progression to death after the onset of symptoms in a patient with hepatic angiosarcoma. Research on early diagnostic strategies and newer therapies are needed to improve prognosis in this rare and poorly understood malignancy with limited treatment options.