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Case Reports in Gastrointestinal Medicine
Volume 2015, Article ID 934784, 6 pages
http://dx.doi.org/10.1155/2015/934784
Case Report

Clinical Outcome of a Portosplenomesenteric Venous Thrombosis in Necrotizing Acute Pancreatitis with Protein C and S Deficiency Treated by Anticoagulation Therapy Alone

1Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde University Teaching Hospital, Yaoundé, Cameroon
2Department of Surgery and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde University Teaching Hospital, Yaoundé, Cameroon
3Department of Radiology and Imaging, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaoundé, Cameroon
4Department of Internal Medicine and Specialties, Faculty of Medicine and Biomedical Sciences, University of Yaounde 1, Yaounde General Hospital, Yaoundé, Cameroon

Received 24 April 2015; Revised 24 August 2015; Accepted 30 August 2015

Academic Editor: Hideto Kawaratani

Copyright © 2015 Firmin Ankouane et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. W. Mohamed, “A case of portal vein thrombosis associated with acute cholecystitis/pancreatitis or coincidence,” Hepatobiliary and Pancreatic Diseases International, vol. 5, no. 2, pp. 308–310, 2006. View at Google Scholar · View at Scopus
  2. H. J. Gonzelez, S. J. Sahay, B. Samadi, B. R. Davidson, and S. H. Rahman, “Splanchnic vein thrombosis in severe acute pancreatitis: a 2-year, single-institution experience,” HPB, vol. 13, no. 12, pp. 860–864, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. J. Easler, V. Muddana, A. Furlan et al., “Portosplenomesenteric venous thrombosis in patients with acute pancreatitis is associated with pancreatic necrosis and usually has a benign course,” Clinical Gastroenterology and Hepatology, vol. 12, no. 5, pp. 854–862, 2014. View at Publisher · View at Google Scholar · View at Scopus
  4. S. S. Badhal, S. Sharma, A. Saraya, and A. K. Mukhopadhyay, “Prognostic significance of D-dimer, natural anticoagulants and routine coagulation parameters in acute pancreatitis,” Tropical Gastroenterology, vol. 33, no. 3, pp. 193–199, 2012. View at Google Scholar · View at Scopus
  5. S. Harris, N. A. Nadkarni, H. V. Naina, and S. S. Vege, “Splanchnic vein thrombosis in acute pancreatitis: a single-center experience,” Pancreas, vol. 42, no. 8, pp. 1251–1254, 2013. View at Publisher · View at Google Scholar · View at Scopus
  6. N. A. Nadkarni, S. Khanna, and S. S. Vege, “Splanchnic venous thrombosis and pancreatitis,” Pancreas, vol. 42, no. 6, pp. 924–931, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. A. J. Lucendo Villarín, G. Carrión Alonso, S. Martín Chávarri, M. Allona Krauel, and J. R. Prado Rodríguez, “Acute pancreatitis and protein C deficiency caused by mesenteric venous thrombosis,” Revista Espanola de Enfermedades Digestivas, vol. 98, no. 7, pp. 553–554, 2006. View at Google Scholar · View at Scopus
  8. V. Pettilä, L. Kyhälä, M.-L. Kylänpää et al., “APCAP-activated protein C in acute pancreatitis: a double-blind randomized human pilot trial,” Critical Care, vol. 14, no. 4, article R139, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. D. Radenković, D. Bajec, A. Karamarkovic et al., “Disorders of hemostasis during the surgical management of severe necrotizing pancreatitis,” Pancreas, vol. 29, no. 2, pp. 152–156, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. O. Lindstrom, L. Kylänpää, P. Mentula et al., “Upregulated but insufficient generation of activated protein C is associated with development of multiorgan failure in severe acute pancreatitis,” Critical Care, vol. 10, no. 1, article R16, 2006. View at Publisher · View at Google Scholar · View at Scopus
  11. S. Parikh, R. Shah, and P. Kapoor, “Portal vein thrombosis,” The American Journal of Medicine, vol. 123, no. 2, pp. 111–119, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. W. Jiang, J. Zhou, L. Ke et al., “Splanchnic vein thrombosis in necrotizing acute pancreatitis: detection by computed tomographic venography,” World Journal of Gastroenterology, vol. 20, no. 44, pp. 16698–16701, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. W.-S. Park, H.-I. Kim, B.-J. Jeon, S.-H. Kim, and S.-O. Lee, “Should anticoagulants be administered for portal vein thrombosis associated with acute pancreatitis?” World Journal of Gastroenterology, vol. 18, no. 42, pp. 6168–6171, 2012. View at Publisher · View at Google Scholar · View at Scopus
  14. A. Plessier, S. Darwish-Murad, M. Hernandez-Guerra et al., “Acute portal vein thrombosis unrelated to cirrhosis: a prospective multicenter follow-up study,” Hepatology, vol. 51, no. 1, pp. 210–218, 2010. View at Publisher · View at Google Scholar · View at Scopus
  15. A. R. Alvi, S. Khan, S. K. Niazi, M. Ghulam, and S. Bibi, “Acute mesenteric venous thrombosis: improved outcome with early diagnosis and prompt anticoagulation therapy,” International Journal of Surgery, vol. 7, no. 3, pp. 210–213, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. T. Opitz, A. B. Buchwald, T. Lorf, D. Awuah, G. Ramadori, and W. Nolte, “The transjugular intrahepatic portosystemic stent-shunt (TIPS) as rescue therapy for complete Budd-Chiari syndrome and portal vein thrombosis,” Zeitschrift fur Gastroenterologie, vol. 41, no. 5, pp. 413–418, 2003. View at Publisher · View at Google Scholar · View at Scopus
  17. S. Vedantham, “Interventional approaches to deep vein thrombosis,” American Journal of Hematology, vol. 87, supplement 1, pp. S113–S118, 2012. View at Publisher · View at Google Scholar · View at Scopus
  18. T. R. Heider, S. Azeem, J. A. Galanko et al., “The natural history of pancreatitis-induced splenic vein thrombosis,” Annals of Surgery, vol. 239, no. 6, pp. 876–882, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. E. Andersson, D. Ansari, and R. Andersson, “Major haemorrhagic complications of acute pancreatitis,” British Journal of Surgery, vol. 97, no. 9, pp. 1379–1384, 2010. View at Publisher · View at Google Scholar · View at Scopus