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Case Reports in Gastrointestinal Medicine
Volume 2016 (2016), Article ID 1053138, 3 pages
Case Report

Agenesis of the Gallbladder in Monozygotic Twin Sisters

Department of Gastroenterology, Aizu Medical Center, Fukushima Medical University, 21-2 Maeda, Tanisawa, Kawahigashi, Aizuwakamatsu 969-3492, Japan

Received 6 November 2015; Accepted 30 December 2015

Academic Editor: R. J. L. F. Loffeld

Copyright © 2016 Koki Hoshi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Agenesis of the gallbladder, a rare anomaly, is generally regarded as an organogenic failure. Several reports suggest that this congenital defect is inherited but that supposition remains controversial. We described agenesis of the gallbladder in identical twins. A 21-year-old female presented with a history of acute pain in the epigastrium and right hypochondrium. Various imaging modalities showed “gallbladder agenesis.” Moreover, her older identical twin sister had also no visualized gallbladder in imaging modalities. This case report strongly suggested that agenesis of the gallbladder would be caused by a genetic abnormality.