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Case Reports in Gastrointestinal Medicine
Volume 2016 (2016), Article ID 7603484, 3 pages
http://dx.doi.org/10.1155/2016/7603484
Case Report

Herpes Simplex Virus-2 Esophagitis in a Young Immunocompetent Adult

1Department of Medicine, Bridgeport Hospital-Yale New Haven Health, Bridgeport, CT 06610, USA
2Department of Gastroenterology, Bridgeport Hospital-Yale New Haven Health, Bridgeport, CT 06610, USA

Received 28 January 2016; Accepted 30 March 2016

Academic Editor: Tetsuo Hirata

Copyright © 2016 Deepak K. Kadayakkara et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Herpes simplex esophagitis (HSE) is commonly identified in immunosuppressed patients. It is rare among immunocompetent patients and almost all of the reported cases are due to HSV-1 infection. HSV-2 esophagitis is extremely rare. We report the case of a young immunocompetent male who presented with dysphagia, odynophagia, and epigastric pain. Endoscopy showed multitudes of white nummular lesions in the distal esophagus initially suspected to be candida esophagitis. However, classic histopathological findings of multinucleated giant cells with eosinophilic intranuclear inclusions and positive HSV-2 IgM confirmed the diagnosis of HSV-2 esophagitis. The patient rapidly responded to acyclovir treatment. Although HSV-2 is predominantly associated with genital herpes, it can cause infections in other parts of the body previously attributed to only HSV-1 infection.