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Case Reports in Gastrointestinal Medicine
Volume 2017, Article ID 2951547, 6 pages
https://doi.org/10.1155/2017/2951547
Case Report

A Calcium Enterolith in a Patient with Crohn’s Disease and Its In Vitro Dissolubility in Citric Acid

1Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
2Department of General Medicine, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
3Central Research Laboratory, Okayama University Medical School, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
4Department of Gastroenterological Surgery, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan
5Department of Endoscopy, Okayama University Hospital, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan

Correspondence should be addressed to Masaya Iwamuro; pj.oc.oohay@ayasamorumawi

Received 27 June 2017; Accepted 9 August 2017; Published 7 September 2017

Academic Editor: Warwick S. Selby

Copyright © 2017 Masaya Iwamuro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The microstructure and dissolubility of a calcified enterolith and enterolith pieces removed from a 26-year-old Japanese woman with Crohn’s disease were analyzed using scanning electron microscopy and energy dispersive X-ray spectroscopy. The enterolith showed a multilayered structure with fatty acid calcium and magnesium phosphate. The amount of calcium, magnesium, and phosphate decreased after they were immersed in a citric acid solution, suggesting a potential contribution of acidic aqueous solution to elute inorganic substances contained in calcified enteroliths. This is the first study to investigate the in vitro dissolubility of calcified enteroliths induced by citric acid solution.