Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Gastrointestinal Medicine
Volume 2017, Article ID 4789259, 5 pages
https://doi.org/10.1155/2017/4789259
Case Report

Gastrointestinal Involvement of Testicular Germ Cell Tumor: A Case Report and Literature Review

1Department of Internal Medicine, Reading Health System, Sixth Avenue and Spruce Street, West Reading, PA 19611, USA
2Hospitalist Services, Reading Health System, Sixth Avenue and Spruce Street, West Reading, PA 19611, USA
3Department of Pathology, Reading Health System, Sixth Avenue and Spruce Street, West Reading, PA 19611, USA

Correspondence should be addressed to Oluwaseun Shogbesan; gro.htlaehgnidaer@nasebgohs.nuesawulo

Received 3 July 2017; Accepted 6 September 2017; Published 10 October 2017

Academic Editor: Yoshihiro Moriwaki

Copyright © 2017 Oluwaseun Shogbesan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. L. Siegel, K. D. Miller, and A. Jemal, “Cancer statistics, 2016,” CA: A Cancer Journal for Clinicians, vol. 66, no. 1, pp. 7–30, 2016. View at Publisher · View at Google Scholar
  2. G. S. Rosenblatt, C. J. Walsh, and S. Chung, “Metastatic testis tumor presenting as gastrointestinal hemorrhage,” Journal of Urology, vol. 164, no. 5, p. 1655, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Nord, S. D. Fossa, and K. E. Giercksky, “Gastrointestinal presentation of germ cell malignancy,” European Urology, vol. 38, no. 6, pp. 721–724, 2000. View at Publisher · View at Google Scholar · View at Scopus
  4. A. Gadodia, I. Ghosh, G. Prakash, S. Thulkar, and V. Raina, “Massive gastro-intestinal haemorrhage in metastatic germ cell tumor from duodenal invasion: a report of two cases,” Tropical Gastroenterology, vol. 32, no. 3, pp. 232–234, 2011. View at Google Scholar · View at Scopus
  5. K. Komori, D. Takahari, K. Kimura et al., “Recovery from choriocarcinoma syndrome associated with a metastatic extragonadal germ cell tumor hemorrhage,” Case Reports in Gastroenterology, vol. 10, no. 1, pp. 193–198, 2016. View at Publisher · View at Google Scholar · View at Scopus
  6. I. Cicin, F. Ozyilmaz, H. Karagol, F. Yalcin, S. Uzunoglu, and M. Kaplan, “Massive upper gastrointestinal bleeding from pure metastatic choriocarcinoma in patient with mixed germ cell tumor with subclinical intestinal metastasis,” Urology, vol. 73, no. 2, pp. 443.e15–443.e17, 2009. View at Publisher · View at Google Scholar · View at Scopus
  7. J. T. Plukker, H. S. Koops, D. T. Sleijfer, J. W. Oosterhuis, and E. D. Van Jagt, “Intestinal hemorrhages in patients with a nonseminomatous testicular tumor,” Cancer, vol. 68, no. 12, pp. 2630–2632, 1991. View at Publisher · View at Google Scholar · View at Scopus
  8. E.-I. Takaoka, K. Kawai, S. Ando, T. Shimazui, and H. Akaza, “Neutropenic colitis during standard dose combination chemotherapy with nedaplatin and irinotecan for testicular cancer,” Japanese Journal of Clinical Oncology, vol. 36, no. 1, pp. 60–63, 2006. View at Publisher · View at Google Scholar · View at Scopus
  9. K. Kawai, S. Imada, K. Iida, S. Tsukamoto, N. Miyanaga, and H. Akaza, “Neutropenic colitis as a complication of high-dose chemotherapy for refractory testicular cancer,” Japanese Journal of Clinical Oncology, vol. 28, no. 9, pp. 571–573, 1998. View at Publisher · View at Google Scholar · View at Scopus
  10. M. Hauptmann, S. D. Fossa, M. Stovall et al., “Increased stomach cancer risk following radiotherapy for testicular cancer,” British Journal of Cancer, vol. 112, no. 1, pp. 44–51, 2015. View at Publisher · View at Google Scholar · View at Scopus
  11. L. B. Travis, S. D. Fossa, S. J. Schonfeld et al., “Second cancers among 40,576 testicular cancer patients: focus on long-term survivors,” Journal of the National Cancer Institute, vol. 97, no. 18, pp. 1354–1365, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Horwich, S. D. Fossa, R. Huddart et al., “Second cancer risk and mortality in men treated with radiotherapy for stage I seminoma,” British Journal of Cancer, vol. 110, no. 1, pp. 256–263, 2014. View at Publisher · View at Google Scholar · View at Scopus
  13. K. Hemminki, H. Liu, and J. Sundquist, “Second cancers after testicular cancer diagnosed after 1980 in Sweden,” Annals of Oncology, vol. 21, no. 7, pp. 1546–1551, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. S. C. Kadakia, A. Parker, and L. Canales, “Metastatic tumors to the upper gastrointestinal tract: endoscopic experience,” The American Journal of Gastroenterology, vol. 87, no. 10, pp. 1418–1423, 1992. View at Publisher · View at Google Scholar · View at Scopus
  15. A. O. Laiyemo, M. Jack, F. W. Dawkins, and D. T. Smoot, “Upper gastrointestinal bleeding from metastatic testicular cancer,” Journal of the National Medical Association, vol. 101, no. 8, pp. 808-809, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. R. Hoffmann, I. Plug, M. McKee et al., “Innovations in health care and mortality trends from five cancers in seven European countries between 1970 and 2005,” International Journal of Public Health, vol. 59, no. 2, pp. 341–350, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. E. W. Stokes and C. Perkins, “Testicular choriocarcinoma. An unusual presentation as occult gastrointestinal blood loss,” Journal of Adolescent Health Care, vol. 10, no. 2, pp. 146–150, 1989. View at Publisher · View at Google Scholar · View at Scopus
  18. H. O. Altamar, G. W. Middleton, T. A. Capozza, B. K. Auge, and C. L. Amling, “Profound anemia from duodenal invasion of metastatic testicular seminoma,” Journal of Urology, vol. 171, no. 1, pp. 344-345, 2004. View at Publisher · View at Google Scholar · View at Scopus
  19. B. Balogun-Ojuri, Y.-M. Lee, V. Save, A. Ibrahim, A. Y. Warren, and N. S. Fearnhead, “A rare case of primary seminoma of the small bowel with lymph node involvement,” Journal of Gastrointestinal Cancer, vol. 42, no. 3, pp. 183–185, 2011. View at Publisher · View at Google Scholar · View at Scopus
  20. M. M. Chait, R. C. Kurtz, and S. I. Hajdu, “Gastrointestinal tract metastasis in patients with germ-cell tumor of the testis,” The American Journal of Digestive Diseases, vol. 23, no. 10, pp. 925–928, 1978. View at Publisher · View at Google Scholar · View at Scopus
  21. J. W. Sweetenham, J. M. Whitehouse, C. J. Williams, and G. M. Mead, “Involvement of the gastrointestinal tract by metastases from germ cell tumors of the testis,” Cancer, vol. 61, no. 12, pp. 2566–2570, 1988. View at Publisher · View at Google Scholar · View at Scopus
  22. M. J. Reilley and L. C. Pagliaro, “Testicular choriocarcinoma: a rare variant that requires a unique treatment approach,” Current Oncology Reports, vol. 17, no. 2, pp. 2–9, 2015. View at Publisher · View at Google Scholar